Ketamine and Therapy
Psychedelics have become a hot issue recently. There are many podcasts, documentaries, books, and television shows that are shining a light on medicines that have been around for decades (like MDMA) and millennia (like psilocybin). Both MDMA and psilocybin (“magic mushrooms”) have been granted a “Breakthrough Status” by the FDA due to the positive outcomes of various studies. According to the Multidisciplinary Association for Psychedelic Studies (2017), “By granting Breakthrough Therapy Designation, the FDA has agreed that this treatment may have a meaningful advantage and greater compliance over available medications for PTSD.” Psilocybin also has been grated FDA Breakthrough Therapy Designation for the treatment of Treatment-Resistant Depression. In August 2024, the FDA rejected MDMA Assisted Psychotherapy and encouraged another Phase 3 study to ensure safety and efficacy.
Ketamine and esketamine (Spravato) have also had increasingly more attention in doctor’s offices across the US due to it’s ability to assist clients in reducing depression and attending to suicidality. Many people are interested in learning if psychedelic assisted psychotherapy is right for them, but not sure where to look for guidance. While both MDMA and Psilocybin remain a Schedule I drug (thus indicating no therapeutic value) and remain Federally illegal, many states have taken measures to decriminalize the substances. Ketamine, however, is legal and attainable off-label through a prescription to address mental health concerns like depression, anxiety, and suicidality. Ketamine has been long used as an anesthetic, but given in lower doses, Ketamine has the ability to act as a rapidly acting anti-depressant.
In collaboration with local doctor's offices, specially trained therapists at Prism Wellness are able to uniquely support clients who are appropriate for Ketamine treatment. Prism Wellness is not a medication provider, nor will providers at Prism Wellness encourage any medication-based treatment. If an individual is medically assessed and cleared for ketamine treatment, the client may choose to work with a KAP trained therapist to assist in preparation and integration of sessions.
Ketamine, nor Spravato, however, are a cure-all or a quick fix, nor will they work for everyone. It is important to note that while it is exciting that Ketamine and other psychedelics have had an influx in published studies and articles, more studies are needed to confirm long-term efficacy and best practices.
Prism Wellness, PLLC has four therapists who are able to provide Ketamine Assisted Psychotherapy, Lesley Kellogg, LCMHC, LCAS, NCC, Madi West, LCMHC, NCC, Emma Socha, LCMHCA, and Eliza Burgess, LCMHCA.
Lesley Kellogg, LCMHC, LCAS, NCC is a trauma-focused psychotherapist who believes in the healing properties that psychedelic assisted therapy can bring to the millions of Americans that suffer from PTSD, depression, and many other mental health conditions. Lesley currently partners with local prescribers to offer KAP to clients wishing to receive support before, during, and after Ketamine sessions to seek out lasting changes.
Lesley has completed 100 hours of training through the Multidisciplinary Association for Psychedelic Studies (MAPS) for MDMA Assisted Psychotherapy, Ketamine Assisted Psychotherapy through Polaris Insight Center, and Preparation and Integration Therapy, and Ketamine Assisted Psychotherapy through Polaris. Lesley continues to pursue in depth and experiential training and actively seeks continuing education through reflecting on research, published books, and podcasts with guest speakers from psychedelic clinical trials.
Lesley equally honors the scientific application of psychedelics as well as the spiritual and ceremonial use. Clients who work with Lesley will explore cultural, spiritual, and natural supports to assist them in their therapeutic journey. Lesley highly values collaboration and maintains reciprocal relationships with a variety of professionals from various backgrounds to promote effective care while honoring culture, race, spirituality, and overall health and wellness.
Lesley is a member of the American Psychedelic Practitioners Association.

Lesley also offers Integration Therapy. Integration Therapy can include reflection of a past experience in an non-ordinary state of consciousness. Mindfully exploring your biopsychosocial world experience can bring light into how factors such as family dynamics, trauma history, race, ethnicity, gender, sexual orientation, beliefs about non-ordinary states of consciousness, etc. prior to an experience can reduce the feelings of anxiety or fear a person may have prior to, during, and after the experience.
Integration work post non-ordinary states of consciousness is a critical part in healing that many people forget. non-ordinary states of consciousness may promote neuroplasticity, meaning our brain's ability to create new pathways in our brain to aid us in creating new, healthy and desired patterns and behaviors. If not reinforced, insights gained during a non-ordinary states of consciousness may be reflected on as a memory, but not implemented into one's life and create a lasting change. Working with an integration professional can promote a client's likelihood of maintaining purposeful change.
Non-ordinary State of Consciousness Integration Therapy includes the following:
- Informed Consent (reviewing expectations of therapy, therapeutic modalities utilized, limitations of care, scope of practice, therapist training/background, therapeutic modalities that may be utilized, etc.)
- Clients may reach out days, months, or years before or after an experience
- Exploring intentions
- Processing journey and reflecting on how to integrate insights into everyday life
- Learn from past challenging experiences i.e. "bad trips"
Integration Therapy does not include:
- Therapist is not present if or when an illegal psychedelic is ingested.
- Therapist does not endorse specific resources.
- Therapist does not recommend or encourage a specific path or medicine.
- Therapist does not provide referrals to "underground" (illegal) psychedelic services.
- Any information received is for educational purposes and not to be misconstrued as medical or legal advice.
Those interested in learning more or licensed therapists seeking employment with Prism Wellness to assist in providing psychedelic assisted therapy can reach out to Lesley at Lesley@PrismwellnessNC.com
Lesley was a guest on the Finding New Waters podcast, through New Waters Recovery in Raleigh, North Carolina. Finding New Waters is hosted by New Waters Recovery Medical Director, Dr. Harold Hong and CEO and Founder, Graham Doerge. Join us as we delve into the transformative world of psychedelics. In this captivating podcast, therapist Lesley Kellogg shares her profound insights on the power of psychedelic-assisted therapy. Discover how these substances open new pathways in the brain, facilitate healing experiences, and offer unique opportunities for personal growth. Learn about integration, therapeutic support, and the importance of individualized approaches. You can find the podcast on Spotify, Apple Podcasts, or YouTube.
Resources
- Multidisciplinary Association for Psychedelic Studies
- www.MAPS.org
- Fireside Project
- www.FireSideProject.org
- Erowid
- https://www.erowid.org/
- ● Alex Belser: The Psychedelic Mystical Experience
- https://www.youtube.com/watch?v=BE80piBCdNs
- Psychedelic Passage
- https://www.psychedelicpassage.com/
- Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety
- https://reader.elsevier.com/reader/sd/pii/S2212144719301206?token=9E44EF880FAD8AE51A19D08678057AA53B793280F6484CE12B83BB33888E17342D1CC90F412331B0F487821203B63F35
- Antidepressant, anxiolytic, and anti-addictive properties of Classic Psychedelics
- https://journals.sagepub.com/doi/pdf/10.1177/2045125316638008
- ● Psychedelic Psychiatry’s Brave New World
- https://www.cell.com/cell/pdf/S0092-8674(20)30282-8.pdf?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867420302828%3Fshowall%3Dtrue
- MDMA-Assisted Psychotherapy: How Different is it from Other Psychotherapy?
- https://maps.org/news-letters/v23n1/v23n1_p10-14.pdf
- A Manual for MDMA-Assisted Psychotherapy in the Treatment of PTSD
- https://maps.org/research/mdma/mdma-research-timeline/4887-a-manual-formdma-assisted-psychotherapy-in-the-treatment-of-ptsd
- Posttraumatic Growth Article (Gorman et al, 2020)
- https://onlinelibrary.wiley.com/doi/full/10.1002/jts.22479
- The influence of therapists’ first-hand experience with psychedelics on psychedelic-assisted psychotherapy research and therapist training (Nielson & Guss, 2018)
- https://akjournals.com/view/journals/2054/2/2/article-p64.xml
- Learning to Let Go: A Cognitive-Behavioral Model of How Psychedelic Therapy Promotes Acceptance
- https://www.frontiersin.org/articles/10.3389/fpsyt.2020.00005/full
- ● This is the ACT inspired work
- https://www.sciencedirect.com/science/article/pii/S2212144719301140
- ● The Center for Optimal Living (Integrative Harm Reduction Psychotherapy training)
- https://www.centerforoptimalliving.com/
- Willoughby Britton and Jared Lindhal have a Meditation Safety Toolbox
- https://www.brown.edu/research/labs/britton/resources/meditation-safety-toolbox
- Drug harms in the UK: a multicriteria decision analysis
- https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(10)61462-6/fulltext
- Project New Day
- https://projectnewday.foundation/about-us/
- The Third Wave
- https://thethirdwave.co/
- ● The PsychonautWIKI
- https://psychonautwiki.org/
- Spirit Pharmacist
- https://www.spiritpharmacist.com
- Psychedelic Liberty Summit
- https://chacruna.net/psychedelic-liberty-summit/
- Remedy Centre
- https://remedycentre.ca/contact-us/
- MAPS MDMA-Assisted Therapy Code of Ethics
- https://maps.org/news/bulletin/articles/436-maps-bulletin-spring-2019-vol-29,-no-1/7710-maps-mdma-assisted-psychotherapy-code-of-ethics-spring-2019
- All NPV Sweden Videos:
- ● https://www.youtube.com/channel/UCPnZFa_ln0VoBWjVZS15LLA\
- The Trip Treatment: Michael Pollen's 2015 New Yorker Article
- https://www.newyorker.com/magazine/2015/02/09/trip-treatment
- Psychologists’ responsibility to society: Public policy and the ethics of political action (Allen & Dodd, 2018)
- https://psycnet.apa.org/record/2018-00350-001
- New research on the action of LSD on serotonin receptors
- https://cen.acs.org/environment/pollution/Crystal-structure-shows-LSDbound/98/i36
- Portraits from LSD Session (historical)
- http://www.openculture.com/2013/10/artist-draws-nine-portraits-on-lsd-during-
- 1950s-research-experiment.html
- Washington Post article on access to psychedelic medicine
- https://www.washingtonpost.com/magazine/2020/09/21/psychedelic-medicinewill-it-be-accessible-to-all/?arc404=true
- Race as an element of "Set and Setting"
- https://akjournals.com/view/journals/2054/4/1/article-p51.xml
- MDMA for PTSD: Mechanisms of action
- https://www.researchgate.net/publication/323631269_MDMAassisted_psychotherapy_for_PTSD_Are_memory_reconsolidation_and_fear_extinction_underlying_mechanisms
- Psychedelics are not liked to mental health problems or suicidal behavior
- https://www.researchgate.net/publication/273154807_Psychedelics_not_linked_to_mental_health_problems_or_suicidal_behavior_A_population_study
- Confrontation with the Unconscious
- https://www.goodreads.com/book/show/18708468-confrontation-with-theunconscious
- Portland Integration Network
- https://www.portlandintegrationnetwork.com/
- Zendo Project
- https://zendoproject.org
- Trust surrender receive, MDMA
- https://www.amazon.com/Trust-Surrender-Receive-Release-Trauma/dp/1619617382
- Listening to Ayahuasca
- https://www.amazon.com/Listening-Ayahuasca-Depression-Addiction-Anxiety/dp/1608684024
- Free Books from MAPS
- https://maps.org/resources/freebooks
- Conscious Medicine
- https://www.amazon.com/Consciousness-Medicine-Indigenous-Entheogens-Expanded-ebook/dp/B07H6Z3JXB
- Ryan Westrum’s Psychedelic Handbook
- https://www.amazon.com/Psychedelics-Integration-Handbook-Ph-DWestrum/dp/173387660X
- “Therapeutic Assessment”
- https://www.therapeuticassessment.com/
- ACT-Psilocybin Therapy for Depression Manual
- https://psyarxiv.com/u6v9y/ A
- Peer-reviewed article describing the approach
- https://www.sciencedirect.com/science/article/pii/S2212144719301218
- Links for YouTube Videos - Elizabeth Nielson produced by NPV Sweden:
- MDMA-Assisted therapy for PTSD: Karolinska Institute
- https://www.youtube.com/watch?v=oebmUaZcN8k&list=UUPnZFa_ln0VoBWjVZS15LLA&index=1
- ● Psilocybin for Alcohol Use Disorder: Karolinska Institute
- https://www.youtube.com/watch?v=I4UFJYpCqkA&list=UUPnZFa_ln0VoBWjVZS15LLA&index=5
- The need for Psychedelic Harm Reduction and Integration in Clinical Settings:
- Colloquium on Psychedelic Psychiatry
- https://www.youtube.com/watch?v=yoqaK9ah7Xs&list=UUPnZFa_ln0VoBWjVZS15LLA&index=14